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  • Journal of Experimental and Clinical Medicine
  • Volume:20 Issue:3
  • Prostat Kanseri Genetiği

Prostat Kanseri Genetiği

Authors : S GÜNEŞ, H BAĞCI, Ş SARIKAYA
Pages : 0-0
Doi:10.5835/jecm.v20i3.147
View : 30 | Download : 10
Publication Date : 2009-12-23
Article Type : Other Papers
Abstract :Genetics of Prostate Cancer Prostate cancer is the most common malignancy among men in Weastern industrialized countries. Despite its high incidence, the molecular and genetic events involved in progression of prostate cancer remain poorly understood. Epidemiological studies have suggested that 5-10% of all prostate cancers are familial, and numerous chromosomal loci have been associated with prostate cancer. This paper describes the genetic alterations in prostate tumorogenesis. Prostat kanseri gelişmiş batı ülkelerinde erkeklerde en sık görülen kanser çeşitlerinden biridir. Prostat kanserinin yüksek insidansına rağmen oluşumundaki moleküler ve genetik olaylar tam olarak aydınlatılamamıştır. Epidemiyolojik çalışmalar bütün prostat kanserlerinin %5-10`nun ailesel olduğunu ve çok sayıda kromozomal lokus ile bağlantılı olduğunu göstermektedir. Bu makalede prostat kanserindeki genetik değişiklikler anlatılmaktadır.
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