The sex dependent changes in volume and volumetrie fractional of the grey and white matters in the cerebral hemispheres of young adults in Sudan

Authors : Wedgan AHMED, Bunyamin SAHIN, Tahir OSMAN, Amani ELFAKI

Pages : 0-0

Doi:10.5835/jecm.v2i31.5000068752

View : 42 | Download : 12

Publication Date : 2014-09-10

Article Type : Other Papers

Abstract :Grey and white matter volumes of the cerebral hemisphere are essential for connectivity and cognitive function of the brain, they varies with sex, age, and health status of subjects. The aim of the present study is to measure the grey and white matter volumes and volume fractions of the cerebral hemispheres to examine the sex differences in young healthy Sudanese population. The study includes 139 healthy Sudanese subjects insert ignore into journalissuearticles values(80 males and 59 females);. Participant’s ages were ranging between 20-39 years old. Magnetic resonance imaging insert ignore into journalissuearticles values(MRI); was performed using a Philips 1.5 Tesla scanner. MRI of the subjects were analysed using the BrainSuite automatic segmentation software. Grey and white matter volumes and the volume fractions of cerebral hemispheres were estimated using the output data of the process. The mean volumes insert ignore into journalissuearticles values(cm 3 ); of the grey matter of right and left cerebral hemispheres of males insert ignore into journalissuearticles values(343.40 and 332.84); were larger than that of the females insert ignore into journalissuearticles values(301.21 and 316.81);, respectively insert ignore into journalissuearticles values(p≤0.05);. The mean volumes of the white matter of right cerebral hemispheres of males were also larger than the females insert ignore into journalissuearticles values(192.54 and 166.46);, respectively insert ignore into journalissuearticles values(p≤0.05);. The mean volumes of the white matter of left cerebral hemispheres of males and females insert ignore into journalissuearticles values(186.32 and 177.81); did not show statistically significant differences between the sexes, respectively insert ignore into journalissuearticles values(p≥0.05);. The mean volume fraction insert ignore into journalissuearticles values(%); of the grey matter of right and left cerebral hemispheres of males insert ignore into journalissuearticles values(64.11 and 64.18); and females insert ignore into journalissuearticles values(64.45 and 64.12); did not show statistically significant differences between the sexes, respectively insert ignore into journalissuearticles values(p≥0.05);. Our findings showed that the volume of the white and grey matters were larger in the males than that of the females. These findings are compatible with the fact that of the body and organ sizes are larger in the males. The most important findings are the volume fraction of the grey and white matters are same in both sexes. This means it is an independent value from the body size of the subject.
Keywords : Automatic segmentation, grey and white matter, magnetic resonance imaging, sex differences

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