Changes in antral follicle count and ovarian volume with age

Authors : Aysegul KAYA, Arif KOKCU, Emel KURTOGLU, Tayfun ALPER, Mehmet Bilge ÇETİNKAYA

Pages : 57-61

View : 33 | Download : 10

Publication Date : 2019-10-31

Article Type : Research Paper

Abstract :0 0 1 9 54 OMU Medical Faculty 1 1 62 14.0 96 800x600 Normal 0 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:`Table Normal`; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:``; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:`Times New Roman`;} W e aimed to ascertain the chronologic age at which these sonographic measurements begin to show a significant difference. The study included 100 women insert ignore into journalissuearticles values(78, aged 19-44 and 22, aged 45-50); menstruated spontaneously and without thyroid disease, diabetes mellitus, hyperprolactinaemia, hypogonadotropic hypogonadism or polycystic ovary syndrome and any gynaecologic surgery. They all underwent sonographic measurement of total antral follicle insert ignore into journalissuearticles values(TAF); count and mean ovarian volume insert ignore into journalissuearticles values(MOV); on the second or third days of menstrual cycle. Then, the women were assigned to 5 groups: group 1, 19–24 years; group 2, 25–29 years; group 3, 30–37 years; group 4, 38-44 years; and group 5, 45-50 years. There was a significant association between chronological age and TAF number insert ignore into journalissuearticles values(r² = 0.328, p < 0.001);. No significant difference was noted in TAF number among the first three groups insert ignore into journalissuearticles values(² = 0.58, p > 0.05);. TAF number was significantly different between groups 3 and 4 insert ignore into journalissuearticles values(Z: -3.463, p < 0.001);, but not between groups 4 and 5 insert ignore into journalissuearticles values(Z: -1.698, p > 0.05);. There was a significant relationship between chronological age and MOV insert ignore into journalissuearticles values(r² = 0.149, p < 0.001);. MOV values did not show a significant difference among the first 4 groups insert ignore into journalissuearticles values(² = 0.58, p> 0.05; ² = 7.87, p > 0.05 respectively);. The MOV of group 5 was significantly different from those of groups 1, 2, 3, and 4 insert ignore into journalissuearticles values(Z: -2.75, p < 0.01; Z: -4.351, p < 0.01; Z: -2.722, p < 0.01; and Z: -2.829, p < 0.01 respectively);. In conclusion, the TAF count decreases significantly beginning at 38 years of age, while MOV decreases significantly beginning at 45 years of age. Thus, there is no significant decrease in the ovarian follicular reserve until the age of 38 years, or in the ovarian volume until the age of 45 years.  0 0 1 260 1482 OMU Medical Faculty 12 3 1739 14.0 96 800x600 Normal 0 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:`Table Normal`; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:``; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:`Times New Roman`;}
Keywords : Age, Ovarian reserve, Ovarian volume, Total antral follicle

ORIGINAL ARTICLE URL