THE ACTIONS OF THE α-MELANOCYTE STIMULATING HORMONE (α-MSH) IN INFLAMMATORY CONDITIONS

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Marmara Medical Journal
Volume:14 Issue:2
THE ACTIONS OF THE α-MELANOCYTE STIMULATING HORMONE (α-MSH) IN INFLAMMATORY CONDITIONS

THE ACTIONS OF THE α-MELANOCYTE STIMULATING HORMONE (α-MSH) IN INFLAMMATORY CONDITIONS

Authors : Berna OKTAR, İnci ALİCAN

Pages : 113-118

View : 44 | Download : 7

Publication Date : 2016-12-03

Article Type : Review Paper

Abstract :Inflammation, a localized response to tissue injury, and disorders characterized by inflammation are difficult problems in clinical medicine. This difficulty stems in large part from incomplete understanding of inflammatory processes and their regulation. Recent development of the knowledge of the role of the central nervous system and neuroendocrine system in the host responses has provided a new view of the capacity of neuronal and soluble mediators in these systems to influence inflammation. One of these mediators is the endogenous neuropeptide a-MSH, which is an N-acetyl tridecapeptide derived from the cleavage of a larger precursor molecule, proopiomelanocortin insert ignore into journalissuearticles values(POMC);. It was originally isolated and characterized from the intermediate lobe of the pituitary and it was first recognized by its effect on skin melanophores in lower vertebrates insert ignore into journalissuearticles values(1);.
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