The effects of low bone mineral density on pain, quality of life and fatigue in patients with epilepsy

Authors : Cagri UNALULUTATAR, Gonca YAZICI SACAKLIDIR, Ipek MIDI, Gulseren Derya AKYUZ

Pages : 286-291

Doi:10.5472/marumj.1009016

View : 33 | Download : 7

Publication Date : 2021-10-27

Article Type : Research Paper

Abstract :Objectives: To investigate the effects of low bone mineral density insert ignore into journalissuearticles values(BMD); on pain, quality of life insert ignore into journalissuearticles values(QoL);, and fatigue in epileptic patients who use anticonvulsants. Patients and Methods: Epileptic patients aged 18 years or older who use anticonvulsant drugs were recruited into the study. Demographic and clinical features were recorded, including the duration of epilepsy, number of anticonvulsants used, previous fracture history and BMD scores. The functional parameters included back pain measured with the visual analogue scale insert ignore into journalissuearticles values(VAS); and brief pain inventory insert ignore into journalissuearticles values(BPI); scale, QoL assessed with the Qualeffo-41 questionnaire, and fatigue assessed with the fatigue severity scale insert ignore into journalissuearticles values(FSS);. Results: Of the 100 patients screened for inclusion in the study, 63 epileptic patients met the inclusion criteria. The mean age and mean disease duration of all participants was 39.5 insert ignore into journalissuearticles values(±11.2); and 19.3 insert ignore into journalissuearticles values(±11.6); years, respectively. The median scores for VAS back pain, VAS low back pain, Qualeffo-41, FSS, pain severity, and pain interference insert ignore into journalissuearticles values(BPI); were significantly higher in patients with secondary osteoporosis compared to patients with normal BMD. There were significant correlations between lumbar spinal BMD and VAS back pain insert ignore into journalissuearticles values(rho = – 0.58, p < 0.0005);, BPI pain severity insert ignore into journalissuearticles values(rho = – 0.56, p < 0.0005);, BPI pain interference insert ignore into journalissuearticles values(rho = – 0.52, p < 0.0005);, Qualeffo-41 insert ignore into journalissuearticles values(rho = – 0.56, p < 0.0005);, and FSS insert ignore into journalissuearticles values(rho = – 0.41, p = 0.001);. Conclusion: Epileptic patients suffering from low BMD showed increased pain, fatigue and impaired QoL. Therefore, BMD measurement should be recommended for the evaluation and management of epileptic patients.
Keywords : Epilepsy, Quality of life, Bone mineral density, Fatigue, Pain

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