Crohn’s disease: Etiology, pathogenesis and treatment strategies

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Marmara Medical Journal
Volume:36 Issue:2
Crohn’s disease: Etiology, pathogenesis and treatment strategies

Crohn’s disease: Etiology, pathogenesis and treatment strategies

Authors : Izel Aycan BASOGLU, Berna KARAKOYUN

Pages : 249-254

Doi:10.5472/marumj.1307982

View : 117 | Download : 142

Publication Date : 2023-05-31

Article Type : Review Paper

Abstract :Crohn’s disease insert ignore into journalissuearticles values(CD);, which can be localized in any part of the gastrointestinal tract, is a disease characterized by an irregular immune response to normal and/or abnormal microbial antigens. Recent studies show many extensive data about the roles of genetic and environmental factors, immune function, and gut microbiota in CD. Although, less invasive biomarkers are currently being developed, the diagnosis of the disease is still based on the endoscopy and histological evaluation of biopsy samples. The most common symptoms are diarrhea, abdominal pain, weight loss, and fatigue. Despite the improvements in the treatment methods in the last decade, there is no definitive treatment since the etiology of CD is not known exactly. Therapeutic strategies focus on reducing inflammation and symptoms, maintaining clinical remission, and improving quality of life.
Keywords : Crohns Disease, Inflammatory bowel disease, Intestinal microbiota, Nutrition therapy

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