THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS

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Middle East Journal of Science
Volume:7 Issue:2
THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS

THREE MSA TOOLS ANALYSIS in DNA and PROTEIN DATASETS

Authors : Fırat AŞIR, Tuğcan KORAK, Özgür ÖZTÜRK

Pages : 89-99

Doi:10.51477/mejs.983750

View : 47 | Download : 8

Publication Date : 2021-12-30

Article Type : Research Paper

Abstract :Multiple sequence alignment insert ignore into journalissuearticles values(MSA); is used to align three or more sequences of DNA, RNA and protein. It is prominent for constructing phylogenetic trees and evolutionary relationships between sequences with regard to similarities and dissimilarities. Variety of multiple sequence alignment tools are available online, each having different methods and parameters to align sequences. In this article three MSA tools; CLUSTALW, SAGA and MAFFT are used for five datasets BALiBASE_R9, DIRMBASE, SABmark and additionally constructed DNABali and ProteinBali for alignment. Result show that for both protein and DNA dataset, MAFFT may be more useful among three of MSA tool used.
Keywords : multiple sequence alignment, MAFFT, SAGA, CLUSTALW

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