The effect of CT-based cardiothoracic ratio on survival of COVID-19 patients

Authors : Burcu AKMAN, Ahmet Turan KAYA, Şirin ÇETİN

Pages : 253-263

Doi:10.18621/eurj.1185361

View : 46 | Download : 13

Publication Date : 2023-03-04

Article Type : Research Paper

Abstract :Objectives: We aimed to investigate the relationship between computed tomography insert ignore into journalissuearticles values(CT);- based cardiothoracic ratio insert ignore into journalissuearticles values(CTR); with mortality rates of COVID-19 patients. Methods: Our study was a single-center retrospective analysis of 484 patients insert ignore into journalissuearticles values(aged ≥ 18); who were admitted to our hospital’s emergency department. We included only laboratory-confirmed COVID-19 patients who underwent chest CT. Data of demographic information, laboratory findings, survivals, and chest CT imaging findings were recorded. The radiologist calculated CTR by dividing the greatest transverse cardiac diameter by the greatest transverse thoracic diameter on the initial chest CT. Cardiomegaly was defined if “CTR > 0.5”. Results: Thirty insert ignore into journalissuearticles values(6.2%); patients were treated as outpatients, and 135/484 insert ignore into journalissuearticles values(%27.9); patients were treated in the intensive care unit insert ignore into journalissuearticles values(ICU);. A total of 147 /484 insert ignore into journalissuearticles values(30.4%); patients died. We found a statistical association between cardiomegaly with mortality rates insert ignore into journalissuearticles values( p < 0.001); and ICU admission insert ignore into journalissuearticles values( p = 0.008);. In multivariate analysis, older age was 1.07-fold insert ignore into journalissuearticles values( p <  0.001);, cardiomegaly 1.75-fold insert ignore into journalissuearticles values( p = 0.015);, history of cerebrovascular diseases 2.929-fold insert ignore into journalissuearticles values( p = 0.018);, and elevated serum LDH level 1.003-fold insert ignore into journalissuearticles values( p = 0.011); associated with higher risks of mortality. Conclusions: Since the presence of cardiomegaly on chest CT is associated with a worse prognosis for COVID-19 patients, more caution should be exercised in the evaluation, follow-up, and treatment of COVID-19 patients with cardiomegaly.
Keywords : COVID 19, computed tomography, chest, cardiothoracic ratio

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