The prognostic implications of a fragmented QRS pattern in patients diagnosed with heart failure

Authors : Ahmet DEMİRKIRAN, Mustafa YİLMAZ, Ömer ŞİT, Adem ATICI, Hasan BARMAN

Pages : 428-436

Doi:10.18621/eurj.1253438

View : 36 | Download : 9

Publication Date : 2023-03-04

Article Type : Research Paper

Abstract :Objectives: The purpose of this study was to investigate the potential association between the presence of a fragmented QRS insert ignore into journalissuearticles values(fQRS); pattern on electrocardiogram insert ignore into journalissuearticles values(ECG); and prognostic outcomes in patients with heart failure insert ignore into journalissuearticles values(HF);. Methods: In the study, 238 patients with a left ventricular ejection fraction of less than 35% were included. The presence of fQRS pattern on ECG was analyzed in all patients. Patients were divided into two groups based on the presence or absence of fQRS on ECG. The primary clinical end points were all-cause mortality and rehospitalization. Results: Baseline demographic characteristics were comparable between the groups. Patients with fQRS had a higher frequency of coronary artery disease and atrial fibrillation insert ignore into journalissuearticles values(72 insert ignore into journalissuearticles values(76%); vs 90 insert ignore into journalissuearticles values(62%);, insert ignore into journalissuearticles values( p = 0.023; 27 insert ignore into journalissuearticles values(29%); vs 25 insert ignore into journalissuearticles values(17%);, insert ignore into journalissuearticles values( p = 0.038, respectively);. Additionally, patients with fQRS had a higher rate of mortality and rehospitalization during the 5-year follow-up period compared to patients without fQRS. insert ignore into journalissuearticles values(30 insert ignore into journalissuearticles values(32%); / 28 insert ignore into journalissuearticles values(19%);, insert ignore into journalissuearticles values( p = 0.028; 56 insert ignore into journalissuearticles values(60%); / 50 insert ignore into journalissuearticles values(35%);, p < 0.001, respectively);. Multivariable logistic regression analysis revealed that the presence of fQRS was independently associated with mortality and rehospitalization insert ignore into journalissuearticles values(insert ignore into journalissuearticles values( p = 0.02 and p < 0.001, respectively);. Conclusions: The results of this study suggest that the presence of fQRS on ECG in patients with HF is independently related to a higher risk of mortality and hospitalization. Therefore, the presence of fQRS may be a useful indicator of poor prognosis in these patients.
Keywords : Fragmented QRS, heart failure, hospitalization, mortality

ORIGINAL ARTICLE URL