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  • Turkish Journal of Analytical Chemistry
  • Cilt: 7 Sayı: 2
  • Synthesis, characterization and antioxidant activity of sulfonyl-1H-1,2,3-triazoles

Synthesis, characterization and antioxidant activity of sulfonyl-1H-1,2,3-triazoles

Authors : Fatih Çelik
Pages : 176-181
Doi:10.51435/turkjac.1665889
View : 40 | Download : 67
Publication Date : 2025-05-31
Article Type : Research Paper
Abstract :3-methoxy-4-((1-tosyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde (3), 4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (6), 4-((1-((4-chloro phenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (9), 4-((4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino)phenol (7), 4-((4-((1-((4-chlorophenyl) sulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzylidene) amino) phenol (10), 4-((4-((1-tosyl-1H-1,2,3-triazol-4-yl) methoxy) benzylidene)amino) phenol (12) were synthesized. The compounds were characterized by FTIR, 1H-NMR and 13C-NMR spectroscopic methods. The antioxidant properties of the compounds were evaluated using two widely accepted methodologies assays (DPPH and FRAP). Compounds 7 and 10 emerged as the most potent antioxidant candidates, displaying the strongest effects in both assays.
Keywords : 1, 2, 3-triazol, , organik sentez, antioksidan aktivite, FRAP yöntemi

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