Investigation of Reproductive Parameters in Male Geriatric (3 years old) Rats

Authors : Volkan KOŞAL, Ömer Faruk KELEŞ, Ahmet Ufuk KÖMÜROĞLU, Yıldıray BASBUGAN
Pages : 174-179
Doi:10.36483/vanvetj.1301038
View : 70 | Download : 60
Publication Date : 2023-07-29
Article Type : Research Paper
Abstract :Many health problems are seen due to aging. One of these is problems in the reproductive system. Reproductive system problems are caused by lower urinary system symptoms, prostate diseases, low fertility, testicular dysfunction. The aim of this study was to compare reproductive parameters of geriatric insert ignore into journalissuearticles values(3 years old); and young insert ignore into journalissuearticles values(3 months old); rats. A 3-year-old rat is equivalent to an average 90-95-year-old human. For this purpose, sperm analysis, testicular and prostate histopathology, testicular oxidative stress parameters were examined in geriatric insert ignore into journalissuearticles values(3 years old); and young insert ignore into journalissuearticles values(3 months old); rats. In the analysis results, it was determined that sperm motility ratio decreased insert ignore into journalissuearticles values(p<0.001);, abnormal sperm ratio increased insert ignore into journalissuearticles values(p<0.001); and sperm density decreased insert ignore into journalissuearticles values(p<0.001); in the geriatric group. Statistically, oxidative stress parameters MDA, AOPP, T-SH levels increased insert ignore into journalissuearticles values(p<0.05); and CAT level decreased insert ignore into journalissuearticles values(p<0.05); in geriatric group. Histopathologically, degeneration, necrosis and irregular alignments were observed in the tubulus seminiferous contortus in the geriatric group. Hyperplasia and dilatation of the prostate gland were detected in the geriatric group. As a result of this study, it is thought that reproductive performance in geriatric male rats is very low, and the probability of reproduction is very difficult.
Keywords : Geriatri, Prostat, Rat, Sperm, Testis

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