Effects of Puerperal Metritis on Uterine Blood Flow, Acute Phase Proteins and Selected Biochemical Parameters in Aleppo Goats

Authors : Ömer Yaprakcı, Tuğra Akkuş

Pages : 187-193

Doi:10.36483/vanvetj.1717699

View : 78 | Download : 217

Publication Date : 2025-11-30

Article Type : Research Paper

Abstract :The aim of this study was to determine the effects of puerperal metritis on uterine blood flow, acute-phase proteins, and certain biochemical parameters in Aleppo goats. In the study, researchers divided 30 multiparous Aleppo goats, which were in the first 10 days postpartum and had not been exposed to any medical treatment, into two equal groups: Group 1 (n=15) included goats with a healthy uterus throughout the postpartum period, whereas Group 2 (n=15) consisted of goats diagnosed with puerperal metritis. Before any intervention, Pulsatility Index (PI) and Resistance Index (RI) were measured using Doppler ultrasonography. Blood samples were then collected to analyze White Blood Cell (WBC) count, Interleukin-6 (IL-6), Tumor Necrosis Factor-Alpha (TNF-α), Serum Amyloid A (SAA), Procalcitonin (PCT), Aspartate Aminotransferase (AST), Gamma-Glutamyl Transferase (GGT), urea, and creatinine levels. The obtained data were evaluated using an independent samples t-test. Body temperature, respiratory rate, heart rate, and WBC values were significantly higher in the puerperal metritis group compared to the control group (p<0.001). In goats with metritis, comparison with the control group revealed that PI and RI values were low (p<0.001), and IL-6, TNF-α, SAA, PCT, AST, GGT, urea and creatinine levels were high (p<0.001). In conclusion, puerperal metritis induces substantial alterations in uterine blood flow and results in marked variations in acute-phase proteins and biochemical markers in goats.
Keywords : Doppler, Keçi, Metritis

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