The Effect of HbA1c Level on Gender-Specific Long-Term Morbidity and Mortality After Isolated Coronary Bypass in Poorly Controlled Diabetic Patients

Authors : Rezan AKSOY, Taylan ADADEMİR, Deniz ÇEVİRME, Ekrem YİLMAZ, Mehmet SENGOR, Cengiz KÖKSAL, Murat RABUS

Pages : 34-41

Doi:10.33808/clinexphealthsci.782816

View : 49 | Download : 11

Publication Date : 2021-03-31

Article Type : Research Paper

Abstract :Objective: The aim of this study is to evaluate the gender specific effects of the high HbA1c levels in poorly controlled diabetic patients undergoing isolated coronary artery bypass grafting insert ignore into journalissuearticles values(CABG); procedure on long term morbidity, mortality and re-revascularization insert ignore into journalissuearticles values(2nd intervention);. Methods: This study was conducted on 532 insert ignore into journalissuearticles values(346 insert ignore into journalissuearticles values(65%); males and 186 insert ignore into journalissuearticles values(35%); females); diabetic patients who underwent CABG procedure at a single center between January 2010 and December 2013.The patients were separated into 4 groups according to gender and preoperative HbA1c level insert ignore into journalissuearticles values(%);. The group1 consisted of females with HBA1c level ≤7insert ignore into journalissuearticles values(n=46);; the group 2 comprised female with HbA1c level >7insert ignore into journalissuearticles values(n=140);; the group 3 comprised men with HbA1c level ≤7insert ignore into journalissuearticles values(n=117);; and the group 4 comprised men with HbA1c level >7insert ignore into journalissuearticles values(n=229);. The groups were analyzed and compared for postoperative complications and mortality. Results: No statistically significant difference was found among the groups in HbA1c levels and gender with respect to postoperative infection and mortality insert ignore into journalissuearticles values(p>0.05);. The HbA1c level was determined to be statically significant and required the 2ndintervention insert ignore into journalissuearticles values(p:0.001; 95% CI: 1.249 insert ignore into journalissuearticles values(1.055,1.478););. Conclusion: This study suggested that there was no difference in mortality rates after CABG among the groups although the current risk calculator modules stated otherwise. However, the HbA1c levels were associated with a need for a secondary intervention on long term follow up period.
Keywords : diabetes mellitus, coronary artery bypass, gender

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