4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST

Authors : M A METWALLY

Pages : 0-0

Doi:10.1501/Commub_0000000407

View : 23 | Download : 10

Publication Date : 1995-01-01

Article Type : Research Paper

Abstract :Condensation of 4- nitrosopyrazolone insert ignore into journalissuearticles values(1); with active methylene components namely, malo- nonitrile, acetophenone, co-cyano-acetophenone and / or 1,3- diphenylacetone gave compounds insert ignore into journalissuearticles values(2a-c); and insert ignore into journalissuearticles values(4);. Treatment of insert ignore into journalissuearticles values(2a, 2b); with hydrazine hydrate gave the aminopyrazoles insert ignore into journalissuearticles values(3a, 3b);. Reaction of insert ignore into journalissuearticles values(1); with some lıydrazines afforded derivatives insert ignore into journalissuearticles values(5, 6, 7a, 7b);. While the condensation of insert ignore into journalissuearticles values(1); with hydrazine hydrate gave the bispyrazolone insert ignore into journalissuearticles values(8);. The structures of the ring systems have been confirmed by their IR, !H-NMR and rnass spectral data.
Keywords : 4 NİTROSO, 1 PHENYL, 3 METHY

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