SYNTHESIS AND INVESTIGATION OF SUBTITUTED 2-AMINOTHIOPHENES FROM SULPHUR AND ACTIVE ME- HYLENE BEARING NITRILES

Authors : Vedia ERTÜZÜN

Pages : 2-18

Doi:10.1501/Commub_0000000277

View : 24 | Download : 8

Publication Date : 1986-01-01

Article Type : Research Paper

Abstract :Benzyl ■ a - cyano cynnamic acid, a nitrile with active methylene group has been synthesized. The reaction of this compound with sulphur in the presence of diethylamine gave 2-Amino-4,5-dıphenyl-3-cyanothiophene. In addition, a similar compound, 2-amino 4-ethyl-5-methyl-3-cyanothiophene has been obtained from sulphur and malonic acid dinitrile using the same amine as catalyst. The both thiophenes and their Schiff’s bases with salicylaldehyde and [3-Hydroxynaphtaldehyde have been investigated by uv, ir and `H-nmr spectroscopy and pKa measurements in terms of substituent and heteroatom effects on various characteristics.
Keywords : SYNTHESIS AND INVESTIGATION, HYLENE BEARING NITRILES, substituent and heteroatom effects

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