Retrospective Clinicopathological Evaluation of Cases Undergoing Radical Orchiectomy: A Single-Center Experience

Authors : Ali Erhan Eren, Selim Taş

Pages : 7-13

Doi:10.54233/endourolbull-1548705

View : 68 | Download : 14

Publication Date : 2025-01-31

Article Type : Research Paper

Abstract :Objective: Testicular tumors, while rare, constitute 1-2% of all male malignancies, with germ cell tumors (GCTs) being the predominant subtype. This study retrospectively evaluates the clinicopathological characteristics of 102 patients who underwent radical orchiectomy for suspected testicular tumors between January 2016 and January 2021 at a single institution. Material and Methods: Data, including demographic details, tumor markers, histopathological findings, and metastasis status, were analyzed. Results: The mean patient age was 34.5 ± 11.5 years, with 51% of tumors located in the right testis. Germ cell tumors were identified in 88% of cases, with seminomas accounting for 46.1%. Conclusion: Non-seminomatous mixed GCTs were found in 32.3% of patients. Notably, 8.8% of cases had a history of cryptorchidism, and lymphovascular invasion was observed in 46% of patients. The study also identified an unexpectedly higher incidence of Sertoli cell tumors, a rare variant of sex-cord stromal tumors, compared to existing literature. These findings contribute to the understanding of the clinicopathological spectrum of testicular tumors and underscore the importance of early diagnosis and treatment.
Keywords : Radikal orşiektomi, Testis tümörü, Seminom

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