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  • European Oral Research
  • Volume:30 Issue:2
  • D3 HİPERVİTAMİNOZUNUN KEMİKLER VE DİŞLERDE MEYDANA GETİRDİĞİ HİSTOPATOLOJİK DEĞİŞİKLİKLER- HISTOPATH...

D3 HİPERVİTAMİNOZUNUN KEMİKLER VE DİŞLERDE MEYDANA GETİRDİĞİ HİSTOPATOLOJİK DEĞİŞİKLİKLER- HISTOPATHOLOGICAL CHANGES OF BONES AND TEEHT DUE TO HYPER VITAMINOSIS OF D3

Authors : M YILDIRIM, Canan ALATLI, Yegane GÜVEN, Çetin KASAPOĞLU
Pages : 75-80
View : 33 | Download : 12
Publication Date : 2012-08-08
Article Type : Research Paper
Abstract :Özet Ds hipemtaminozunun çene kemikleri, uzun kemikler ve dişle üzerindeki etkilerinin araştırıldığı bu çalışma­da 20 Wistar tipi sıçan kullanıldı. Her biri beşer sıçan­dan oluşan döt grubun ilkine D 3 vitamini enjeksiyonu, ikincisine prophylene glycol insert ignore into journalissuearticles values(PG); enjeksiyonu uygula­narak normal dietle beslendi. Üçüncü grup D3 vitami­ninden zengin dietle beslendi. Kontol grubu olan dör­düncü gruba hiçbir uygulama yapılmadı. Beş haftalık deney süresi sonunda öldürülen hayvanların çene ke­mikleri, Ön ve azı dişleri ile uzun kemiklerinden hazır­lanan parafin kesitler ışık mikroskobunda incelendi. Çene kemikleri ve uzun kemiklmerde, kemik trabekül-leri, kemik îliği ve uzun kemiklerde epifiz kıkırdağı de­ğerlendirildi. Dişlerde de dentin kanalları, pulpa odontoblastlar, periodontal aralık ve apikal bölge araş­tırıldı. Sonuç olarak dişlerde ve kemiklerde saptanan patolojik değişikliklerin kaynaklar ile uygunluk göster­diği saptandı. Anahtar sözcükler: Dj hipervitaminozu, histo patoloji, sıçan, kemik, diş, periodontal doku. Abstract 20 Wistar rats mere used in this study, in which the effects oj D 3 hypervitaminosis on jaws, long bones and teeth were in­vestigated. The rats were divided into four groups, each consisting affive rats. Vitamin D3 injection was ferformed in the first group, and propylene glycok insert ignore into journalissuearticles values(PG); in the second. These rast were fed with normal diet The rats in the third group were fed with a diet rich in vitamin D3. No special application was made in the fourth group, which was used as control. At the end of jive weeks Hie rats were sacrified. Paraffin secitons of the jaw, incisors, molars and tibias we­re prepared and examined under light microscope. Bone trabecules and bone marrow were evaluated both in jaws and long bones. Epiphysial, cartilage was also investigated in the long bones. Dentin tubules, pulp odontoblasts, perio­dontal and apical reginos of the teeth was examined as well. Histopatological features were compared wiflt those of lite­rature and discussed. In conclusion, the histopathological changes found in bom and teeth due to D 3 hypervitaminosis were similar to those of literature. Key words : Hypervitaminosis D3, histopatholoyg, rats, bo­ne, teeth); periodontal tissue.  
Keywords :

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