Cerrahpaşa Medical Faculty Hospital HIV-1/-2 Serological Test Data: 2019-2022 Retrospective Evaluation

Harika Öykü DİNÇ; Elif KESKİN; Banu TUFAN KOÇAK; Bekir KOCAZEYBEK

doi:10.26650/experimed.1191760

Cerrahpaşa Medical Faculty Hospital HIV-1/-2 Serological Test Data: 2019-2022 Retrospective Evaluation

Authors : Harika Öykü DİNÇ, Elif KESKİN, Banu TUFAN KOÇAK, Bekir KOCAZEYBEK

Pages : 215-218

Doi:10.26650/experimed.1191760

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Publication Date : 2022-12-31

Article Type : Research Paper

Abstract :Objective: The aim of this study was to retrospectively discuss the human immunodeficiency virus insert ignore into journalissuearticles values(HIV); scanning and verification test results and demographics of patients who were admitted to the Istanbul University Cerrahpaşa Medical Faculty’s Medical Microbiology Laboratory Center Serology/ELISA division with suspected HIV infection or pre-operative serologic screening. In addition, the study aimed to compare HIV seroprevalence with data from the center’s previous period. Materials and Methods: HIV-1/-2 antibody +P24 antigen insert ignore into journalissuearticles values(HIV-1/-2 Ab/Ag); was studied routinely using the chemiluminescent microparticle immunoassay insert ignore into journalissuearticles values(CMIA); method with the same method also being used as the second repeat test. The sera verifications of patients who showed repeated reactivity after the HIV Ab/Ag test were studied using the line immunoassay insert ignore into journalissuearticles values(LIA); method. Results: The study retrospectively studied 156,542 cases between 2019-2022, of which 237 insert ignore into journalissuearticles values(0.17%); showed repeated anti-HIV-1/-2 reactivity. From the repeated reactivity serum samples, LIA testing was performed to confirm the remaining 181 serum samples after excluding the previously confirmed samples, with 175 insert ignore into journalissuearticles values(96.6%); coming back positive. All these samples showed sgp120 and gp41 band positivity, thus confirming HIV1 positivity. Conclusion: These retrospective data from one center regarding HIV seroprevalence for the 2019-2022 period are in line with other national studies. However, due to the COVID-19 pandemic, HIV prevalence during this period may have been higher than detected. HIV prevalence in Istanbul, being a cosmopolitan city that receives immigrants, should be monitored in the future.
Keywords : HIV 1 2, CMIA, LIA, Serological Diagnostic

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