Does Microalbuminuria has Positive Predictive Value in Patients With Essential Hypertension for Renovascular Hypertension?

Authors : Zülfükar YILMAZ, İdris ORUÇ, Yaşar YILDIRIM, Fatma Yılmaz AYDIN, Emre AYDIN, Ali Kemal KADİROGLU, Mehmet Emin YILMAZ
Pages : 16-23
View : 37 | Download : 15
Publication Date : 2013-06-01
Article Type : Research Paper
Abstract :Background: Renovascular disease is an important correctable cause of secondary hypertension. We aimed to research whether microalbuminuria might be an indicator for renovascular hypertension among the essential hypertensive patients. Method: 330 essential hypertensive patients were enrolled to the study. Patients were divided into 2 groups: group 1 insert ignore into journalissuearticles values(microalbuminuria); and group 2 insert ignore into journalissuearticles values(normoalbuminuria);. Urine albumin concentrations were measured by nepholometry after 24-hour urine collection. All subjects were examined by renal duplex doppler ultrasonography and who had renal artery stenosis then MR angiography was performed. Results: Microalbuminuria was detected in 107 of 330 essential hypertensive patients insert ignore into journalissuearticles values(32.42%);. Mean CrCl levels insert ignore into journalissuearticles values(108,14±19,83 vs 116,36±18,62, p=0,002); were significantly lower in the group of patients with microalbuminuria. 3/107 insert ignore into journalissuearticles values(2.80%); of the patients had renal artery stenosis in the group of patients with microalbuminuria and 8/223 insert ignore into journalissuearticles values(3.58%); of the patients had renal artery stenosis in the group of patients with normoalbuminuria. This study showed a sensitivity of 2.8%, specificity 96.41%, positive predictive value 27.27%, negative predictive value 67.40%. Conclusion: We suggest that microalbuminuria isn’t an indicator for renovascular hypertension in patients with essential hypertension.
Keywords : Renovascular hypertension, essential hypertension, microalbuminuria, renal doppler ultrasonography

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