Evaluation of Staphylococcus aureus Infections in Children

Authors : Gülsüm ALKAN, Hatice TÜRK DAĞI, Melike EMİROĞLU, Rumeysa İPTEŞ, Şadiye Kübra TÜTER ÖZ, Meltem KIYMAZ, Muslu Kazım KÖREZ

Pages : 53-60

Doi:10.21765/pprjournal.1306689

View : 76 | Download : 88

Publication Date : 2023-07-31

Article Type : Research Paper

Abstract :Aim: Staphylococcus aureus is the most common infectious agent worldwide which leads to morbidity and mortality. Community and hospital acquired infections can range to skin infections to life-threatening infections. In our study, we attempted to evaluate demographic, clinical, and laboratory parameters and the prognosis of children with S. aureus infection. Methods: Children infected with S. aureus at the Department of Paediatric Infectious Disease, Selcuk University Faculty of Medicine, from 2014 to 2022 were analysed retrospectively. Patients were evaluated for MRSA, MSSA, and community or hospital-acquired infections. Results: A total of 116 children\`s detected specimens were collected; 31.9% contained MRSA and 68.1% contained MSSA. The proportion of community-acquired insert ignore into journalissuearticles values(CA); infections was 88.8%, while hospital-acquired insert ignore into journalissuearticles values(HA); infections were 11.2%. MSSA was more common in the CA-S. aureus group, while MRSA was more common in the HA-S. aureus group insert ignore into journalissuearticles values(p=.025);. The most common clinical manifestations included soft tissue infection, lymphadenitis, cutaneous infection, osteomyelitis, and septic arthritis. Each patient was treated with antibiotics, 77.59% of patients was required hospitalization. In 62.9% of the patients, surgical intervention insert ignore into journalissuearticles values(drainage or debridement); was performed. Despite 86.2% of the patients were cured, infection persisted in nine patients with epidermolysis bullosa, CIPA syndrome, and bone implants. One patient with shunt meningitis died. Conclusions: S. aureus cause both CA and HA superficial or invasive infections, in children. Especially in life-threatening infections, appropriate antibiotic therapy is critical for preventing mortality until an antibiogram culture result is obtained. The patient\`s clinical condition and regional antibiotic resistance should be considered when prescribing antibiotics empirically.
Keywords : Çocuk, invaziv enfeksiyonlar, Staphylococcus aureus, deri ve yumuşak doku enfeksiyonları

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