Investigation of the antimicrobial activity of herbal cream prepared with aqueous extracts of walnut (Juglans regia L.) leaves and shells

Authors : Müjgan Arslan, Adem Önal, Bilge Hilal Çadırcı, Sedanur Gökçe, Mustafa Şimşek

Pages : 149-154

Doi:10.53445/batd.1809617

View : 56 | Download : 92

Publication Date : 2025-12-30

Article Type : Research Paper

Abstract :This study investigated the antimicrobial properties of creams we developed using aqueous extracts from the bark and leaves of walnut (Juglans regia L.), a plant used for therapeutic purposes in traditional folk medicine, at various concentrations and formulations. The antimicrobial activity of the extracts was investigated against Candida species (Candida albicans, Candida utilis) and Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes) using the disk diffusion method. It has been observed that the cream formulation developed with leaf and leaf-bark mixture has significant activity on Candida albicans. In addition, creams derived from the aqueous extract were observed to be active against all microorganisms at various concentrations. As a results, the laboratory demonstration of the antimicrobial activity of a semi-solid cream formulation prepared with walnut shell and leaf extracts is promising for the development of plant-based, low-side-effect, and economical treatment alternatives.
Keywords : Ceviz, geleneksel tıp, tıbbi bitki, topikal krem, antimikrobiyal aktivite

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