Do Antiplatelet Drugs Use Contribute to Clinical Outcomes in Patients Receiving Penile Low- Intensity Shock Wave Therapy (Li-SWT) for Erectile Dysfunction?

Authors : Serdar GEYİK, Mutlu DEGER, Nebil AKDOGAN, Nâzım Abdülkadir KANKILIÇ, İsmail Önder YILMAZ, İbrahim Atilla ARIDOĞAN

Pages : 194-198

Doi:10.36516/jocass.1247105

View : 65 | Download : 64

Publication Date : 2023-08-31

Article Type : Research Paper

Abstract :Aim: Low-intensity extracorporeal shock wave therapy insert ignore into journalissuearticles values(Li-SWT); is one of the recommended treatment options in patients with erectile dysfunction insert ignore into journalissuearticles values(ED);. Li-SWT is safe in patients using antiplatelet drugs insert ignore into journalissuearticles values(APs);, however, there are no specific studies on the contribution of APs use to clinical improvement in erectile function. We aimed to evaluate the early clinical results of Li-SWT administration and whether the use of APs had an additional positive contribution to clinical improvement and safe in ED patients. Methods: Patients with ED for more than 6 months despite using insert ignore into journalissuearticles values(5 mg/day); PDE5i were included in our study. Patients treated with Li-SWT and using PDE5i were classified as Group 1, patients treated with Li-SWT and using APs and using PDE5i were considered Group 2. The evaluation results of the International Index of Erectile Function-Erectile Function Areainsert ignore into journalissuearticles values(IIEF-EF); in all patients baseline and after treatment were examined. Results: There are 25 patients in each group. Analysis of IIEF-EF scores showed significant increases in both groups after treatment [group 1 insert ignore into journalissuearticles values(p=0.001);; group 2 insert ignore into journalissuearticles values(p=0.001);]. When the IIEF-EF scores of the groups before and after the treatment were compared with each other; it was shown that baseline scores were similarinsert ignore into journalissuearticles values(p=0.746); and that APs use had no statistically significant effect on post-treatment scores insert ignore into journalissuearticles values(p=0.613); No side effects were seen in APs. Conclusions: This study showed that penile Li-SWT significantly increases the IIEF-EF scores and response of insert ignore into journalissuearticles values(5 mg/day); PDE5i in ED patients and safe, also in AP users. However, Using AP in Li- SWT does not contribute positively to clinical results.
Keywords : Erectile dysfunction, Antiplatelet, Endothelial dysfunction, Low intensity extracorporeal shock wave therapy, Phosphodiesterase type 5 inhibitor

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