The Relationship Between Mean Platelet Volume/Platelet Count (MPV/ PLT) Ratio and Peripheral Artery Disease

Authors : Serhat ÇALIŞKAN, Ferit BÖYÜK

Pages : 76-81

Doi:10.54005/geneltip.1217304

View : 57 | Download : 13

Publication Date : 2023-02-28

Article Type : Research Paper

Abstract :Background/Aim: In our study, we aimed to evaluate the effect of mean platelet volume/platelet count ratio on the development of peripheral artery disease insert ignore into journalissuearticles values(PAD); by comparing it with the control group. Material and Methods: A total of 115 patients with peripheral artery disease as a result of lower extremity color Doppler ultrasonography examination in our hospital were included in the study as the patient group and 100 individuals without peripheral artery disease as the control group. Results: History of coronary artery disease insert ignore into journalissuearticles values(p<0.001);, diabetes mellitus insert ignore into journalissuearticles values(p=0.009);, hypertension insert ignore into journalissuearticles values(p<0.001); and smoking history insert ignore into journalissuearticles values(p<0.001); were significantly higher in the PAD group than in the control group. Serum glucose insert ignore into journalissuearticles values(121.27±25.66 vs. 104.81±34.77; p<0.001);, MPV levels insert ignore into journalissuearticles values(9.99±0.79 vs. 9.04±0.7; p<0.001); and MPV/PLT ratio insert ignore into journalissuearticles values(0.041±0.07 vs. 0.037±0.006, p< 0.001); were found to be significantly higher in the PAD group than in the control group. Serum HDL levels insert ignore into journalissuearticles values(45.03±11.5 vs. 48.67±12.52 p=0.026); were significantly lower in the PAD group than in the control group. In multivariate analysis, age, MPV and MPV/PLT ratio were determined as independent predictors for peripheral arterial disease. Conclusion: In our study, we found that MPV and MPV/PLT ratio were independent predictors of peripheral artery disease.
Keywords : Periferik arter hastalığı, Trombosit aktivasyonu, Ortalama Trombosit Hacmi, Ortalama Trombosit Hacmi Platelet Sayısı Oranı

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