Evaluation of preeclampsia outcomes in de novo preeclampsia and superimposed preeclampsia: A case-control study from a tertiary center

Authors : Göksun İpek, Atakan Tanacan, Zahid Ağaoğlu, Ayça Peker, Gülcan Okutucu, Dilek Sahin
Pages : 274-278
Doi:10.38136/jgon.1440611
View : 89 | Download : 78
Publication Date : 2024-12-28
Article Type : Research Paper
Abstract :Objective: To compare de novo and superimposed preeclampsia outcomes and evaluate the role of chronic hypertension in preeclampsia outcomes Methods: The present retrospective case-control study was conducted on 250 pregnant women diagnosed with preeclampsia, including 100 patients in the superimposed preeclampsia group, 150 in the de novo preeclampsia group. The control group comprised 200 low-risk pregnant women consecutively delivered in the same timeline. De novo and superimposed preeclampsia groups’ demographic specialties and obstetric and neonatal outcomes were compared with the control group and also compared between preeclampsia groups. Parameters were then evaluated with the literature findings. Results: Early onset preeclampsia and preterm delivery rates were higher in the superimposed preeclampsia group , with p-values 0.046 and 0.026, respectively, The presence of prodromal symptoms was lower in the superimposed preeclampsia group than in the de novo preeclampsia group (p=0.029). Fetal growth retardation was higher in both preeclampsia groups then in the control group with a p-value of <0.001. Severe preeclampsia rates were similar in the preeclampsia groups with a p-value of 0.278. Conclusion: The presented study showed in a single tertiary center experience that chronic hypertension is an individual risk factor for early-onset preeclampsia occurrence and preterm delivery. Because the prodromal symptoms are seen less in a superimposed preeclampsia group than in the de novo preeclampsia group, obstetricians must be careful with severe preeclampsia in such specific patient group.
Keywords : süperempoze preeklampsi, preeklampsi sonuçları, olumsuz gebelik sonuçları, kronik hipertansiyon

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