Impact of Nasal MRSA Colonization on Surgical Site Infections After Neurosurgical Procedures

Home Page
About
Submit A Journal
Submit A Conference
Submit Paper/Book
- Submit a Preprint
- Submit a Book
Contact

Maltepe Tıp Dergisi
Cilt: 17 Sayı: 2
Impact of Nasal MRSA Colonization on Surgical Site Infections After Neurosurgical Procedures

Impact of Nasal MRSA Colonization on Surgical Site Infections After Neurosurgical Procedures

Pages : 49-53

View : 45 | Download : 48

Publication Date : 2025-08-31

Article Type : Research Paper

Abstract :Aim: This study aimed to evaluate the prevalence of nasal Methicillin-resistant Staphylococcus aureus (MRSA) carriage among patients undergoing spinal surgery and to investigate its association with postoperative surgical site infections (SSIs). Materials and Methods: A total of 120 patients scheduled for elective spinal surgery were prospectively screened for nasal MRSA colonization via preoperative nasal swabs. Patients were monitored for the development of postoperative SSIs. The cohort was divided into MRSA-positive and MRSA-negative groups, and infection rates were compared using Fisher’s exact test. Antibiotic prophylaxis protocols were applied uniformly across all patients. Results: Among the 120 patients, 15 (12.5%) were identified as nasal MRSA carriers. Postoperative SSIs occurred in 2 of the 15 MRSA-positive patients (13.3%) and in 2 of the 105 MRSA-negative patients (1.9%). Fisher’s exact test revealed a statistically significant association between nasal MRSA carriage and postoperative infection risk (p = 0.048). The odds of developing a postoperative SSI were 7.7 times higher in MRSA carriers compared to non-carriers. Discussion: The MRSA colonization rate in our spinal surgery cohort was higher than reported in some general surgical populations. The significantly elevated SSI rate among MRSA carriers highlights the clinical importance of preoperative screening and potential decolonization strategies in high-risk spinal procedures. These findings support the inclusion of MRSA status in perioperative risk stratification. Conclusion: Preoperative nasal MRSA colonization is significantly associated with increased postoperative SSI risk in spinal surgery. Routine MRSA screening and decolonization may be beneficial in reducing infectious complications in this patient population.
Keywords : : MRSA, nazal kolonizasyon, cerrahi alan enfeksiyonu, profilaksi

ORIGINAL ARTICLE URL

* There may have been changes in the journal, article,conference, book, preprint etc. informations. Therefore, it would be appropriate to follow the information on the official page of the source. The information here is shared for informational purposes. IAD is not responsible for incorrect or missing information.