Predicting Cardiovascular Risk In Prediabetes Status: The Role Of Atherogenic Plasma Index In Individuals With Impaired Fasting Glucose

Authors : Hakan ŞIVGIN

Pages : 796-804

Doi:10.20515/otd.1345956

View : 37 | Download : 38

Publication Date : 2023-09-27

Article Type : Research Paper

Abstract :Atherogenic plasma index insert ignore into journalissuearticles values(API); is a relatively new index used in the general population for predicting the risk of cardiovascular disease. High fasting plasma glucose insert ignore into journalissuearticles values(FPG); levels have been shown to be associated with diabetes mellitus and metabolic syndrome, and API. However, no study has been conducted on the relationship between impaired fasting glucose identified using fasting and 2-hour plasma glucose in the oral glucose tolerance test, hemoglobin A1c insert ignore into journalissuearticles values(HbA1c); levels, and API. API was calculated using the logarithm of the molar ratio of triglycerides to high-density lipoprotein cholesterol. The relationship between glucose metabolism parameters with diabetes status and API was analyzed. The frequency of prediabetes and diabetes in the study participants was 35.3% insert ignore into journalissuearticles values(n=58); and 25.3% insert ignore into journalissuearticles values(n=40);, respectively. 40 individuals were identified as Type 2 diabetes insert ignore into journalissuearticles values(fasting glucose >125 mg/dl, OGTT 2nd hour >200 mg/dl);, 58 as impaired fasting glucose insert ignore into journalissuearticles values(IFG); prediabetes insert ignore into journalissuearticles values(fasting glucose: 100-125 mg/dl, OGTT 2nd hour <140mg/dl);, and 66 individuals as a non-diabetic control group insert ignore into journalissuearticles values(glucose <100 mg/dL);. 28.1% of participants were in the low-risk group insert ignore into journalissuearticles values(API<0.11);, 18.2% were in the medium-risk group insert ignore into journalissuearticles values(API 0.11-0.21);, and 53.6% were in the high-risk group insert ignore into journalissuearticles values(API>0.21);. High API insert ignore into journalissuearticles values(high-risk group); was found to be significantly associated with prediabetes and diabetes status. API was also significantly associated with HbA1c, FPG, and 2-hour plasma glucose levels in the OGTT. AIP was significantly associated with the param¬eters of diabetes and prediabetes. Simple calculations made from fasting lipid panel results can be provide more information in assessing the risk of cardiovascular disease with IFG patients in prediabetes status.
Keywords : Aterojenik Plazma İndexi, Prediyabet, Diabetes mellitus, Dislipidem