Evaluation of Clinical and Microbiological Features of Intraabdominal Abscesses in A Tertiary Hospital in Türkiye

Authors : Suzan Şahin, Bülent Kaya, Serap Demir Tekol

Pages : 277-284

Doi:10.20515/otd.1592621

View : 4 | Download : 1

Publication Date : 2025-02-27

Article Type : Research Paper

Abstract :Knowing the causative agents and microbiological susceptibility in intra-abdominal abscess (IAA) cases guides empirical antibiotic selection. We aimed to investigate the causative agents, susceptibility, and treatment options in intra-abdominal abscesses. Patients hospitalized with intra-abdominal abscesses between January 2020 and December 2022, in whom abscess material cultures yielded growth, were retrospectively analyzed. Risk factors, causative agents, antibiotic susceptibilities, and treatment options were evaluated. A total of 43 patients, with a mean age of 57.2 years (range 22-88), consisting of 30 males (69.8%) and 13 females (30.2%), were included in the study. Eleven patients had no underlying diseases, while gastrointestinal conditions constituted the majority of underlying diseases (n=11, 25.6%). The most common site of abscess was the liver (n=19, 44.2%), followed by intraperitoneal (n=14, 32.6%), retroperitoneal (n=5, 11.6%) regions. The most frequently used imaging method was computed tomography (CT) in 29 patients (67.5%). A total of 60 microorganisms were isolated from the 43 patients included in the study. The majority of the isolated microorganisms were Gram-negative bacteria (n=42, 70.0%). In 15 patients (34.9%) who initially received empirical antibiotic treatment, the treatment was subsequently modified to broad-spectrum antibiotics based on the resistance profile of the isolated microorganism. In patients monitored for intra-abdominal abscesses, initiating appropriate empirical antimicrobial therapy before culture results become available can be crucial. Once the infectious agent is identified and its resistance profile determined, targeted treatment can be administered. Each institution’s awareness of its own antibiotic resistance patterns will guide empirical therapies effectively.
Keywords : intra-abdominal apse, tedavi, direnç