RISK FACTORS ASSOCIATED WITH PRETERM PREMATURE RUPTURE OF MEMBRANES

Authors : İsa Temur, Enes Karaman

Pages : 8-13

Doi:10.34108/eujhs.1559678

View : 140 | Download : 131

Publication Date : 2025-04-07

Article Type : Research Paper

Abstract :Preterm premature rupture of membranes is an important obstetric problem that has a profound impact on birth, neonatal mortality and morbidity and therefore requires urgent intervention. In this study, 100 cases and 100 control subjects who applied to a tertiary university hospital were included. Possible risk factors included gravidity, age, smoking, body mass index, time since the previous pregnancy, birth history, socioeconomic status, education level, caffeine consumption, urinary tract infection, and a history of previous abortion.The case and control groups were statistically compared based on risk factors. Based on the results there was a statistically significant difference between the case and control groups with respect toliteracy, obesity, urinary tract infections, history of abortion, multiparity, previous birth was before two years, and history of premature birth(p=0.033, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, respectively).However, no significant difference was observed regarding age range, number of births, birth type, and coffee use (p=0.334, p=0.131, p=0.057 and p=0.077). As a result of binominal regression analysis, the highest risk was found for obesity (OR=7.63; 95% confidence interval, 1.68–34.66), urinary tract infection (OR=3.57; 95% confidence interval, 1.43–8.93), previous birth less than two years (OR=7.53; 95% confidence interval, 2.85–19.9), previous preterm birth (OR=13.42; 95% confidence interval, 3.62–49.82), smoking/alcohol use (OR=15.97; 95% confidence interval, 4.99–51.1) (p<0.05).Smoking/alcohol consumption and history of previous preterm birth were the most important risk factors.
Keywords : Erken doğum, preterm prematür membran rüptürü, risk faktörleri