10-Year Cardiovascular Risk, Serum Lipid Indices and High Sensitivity CRP in a Healthy Population

Authors : Sinan AKINCI, Ertan AKBAY

Pages : 225-231

Doi:10.31832/smj.1166369

View : 101 | Download : 22

Publication Date : 2023-06-30

Article Type : Research Paper

Abstract :Objective: It is very important to identify individuals at high risk of atherosclerotic cardiovascular diseases insert ignore into journalissuearticles values(ASCVD); and for this purpose, many risk calculation tools and parameters are used. In this study, we aimed to investigate the correlation between the ACC/AHA cardiovascular risk and serum lipid indices and high sensitivity C-reactive protein insert ignore into journalissuearticles values(hs-CRP); in a healthy population. Methods: Our study was conducted retrospectively on individuals aged between 40 and 79 years and with sufficient data, using the hospital database. Patients with a history of any chronic disease and active infection were excluded. Individuals were analyzed by grouping them into low insert ignore into journalissuearticles values( 5%); estimated 10-year risk of ASCVD. Results: 184 individuals with a median age of 46 and 37.5% women were included in the study. The median 10-year estimated risk of ASCVD in the study population was 3% insert ignore into journalissuearticles values(1.3/5.98);. The low-risk group had a significantly lower atherogenic index of plasma insert ignore into journalissuearticles values(AIP);, Castelli I risk index insert ignore into journalissuearticles values(CR-I);, and Castelli II risk index insert ignore into journalissuearticles values(CR-II); compared to the borderline to high-risk group insert ignore into journalissuearticles values(p <0.001 for all);. However, CRP was not different between groups insert ignore into journalissuearticles values(p: 0.683);. The 10-year risk of ASCVD was statistically significantly correlated with AIP insert ignore into journalissuearticles values(R:0.380; p<0.001);, CR-I insert ignore into journalissuearticles values(R:0.467; p<0.001);, and CR-II insert ignore into journalissuearticles values(R:0.482; p<0.001);, but no correlation was detected with hs-CRP insert ignore into journalissuearticles values(R:0.065; p:0.381);. Conclusion: The lack of correlation between ACC/AHA\`s risk calculation tool and hs-CRPsuggests that hs-CRP cannot be used as a high-risk indicator in these individuals or that this tool is insufficient to detect some high-risk patients.
Keywords : C Reaktif Protein, Kardiyovasküler Risk Skoru, Dislipidemiler

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