Comparison of Galactography, Ultrasonography and Contrast Enhanced Magnetic Resonance Imaging Findings with Pathology Results in Patients with Pathologic Nipple Discharge

Authors : Serap Doğan, Emel Durmuş, Figen Öztürk

Pages : 191-201

Doi:10.31832/smj.1430107

View : 62 | Download : 83

Publication Date : 2024-06-30

Article Type : Research Paper

Abstract :Objective: The purpose of this study was to evaluate the lesion detection rates of imaging methods by comparing galactography, ultrasonography (US) and contrast enhanced-magnetic resonance imaging (CE-MRI) findings with pathology results in patients with pathologic nipple discharge (PND). Materials and Methods: Fifty-two female patients (age range, 18–79 years; mean age, 49,12 years) with PND were included the study. Radiologic imaging and pathology results of patients were evaluated retrospectively. The lesion detection rates of galactography, US and CE-MRI were evaluated. Galactography findings were evaluated according to modified Galactogram Image Classification System (GICS) and compared with the pathology results. Results: Galactography was applied in 48 patients. While in 45 (93.8%) of 48 patients lesion that causes PND was found on galactography. All of the patients had breast US. In 48 (92.3%) patients, causing lesion was found on US. CE-MRI was performed in 33 of 52 patients, and lesion was found in 30 patients (90.9%). Lesion detection rates of galactography, US and CE-MRI findings were similar. Pathology results of 48 patients (92.3%) were benign, and the results of 3 patients (5.8%) were malignant. The result of 1 patient (2%), there was no lesion on pathologic examination. The sensitivity of galactography, US and CE-MRI were 93.6%, 92.2% and 90.6%, respectively. In the double and triple combinations of imaging methods regarding the lesion detection, sensitivity was found as 100%. There was no significant relationship between modified GICS scores and pathology results. Conclusion: Galactography, US and CE-MRI have high sensitivity for lesion detection in patients with PND. When galactography, US and CE-MRI findings are used in double and triple combinations, lesion detection rates could be increase.
Keywords : Meme başı akıntısı, Meme Manyetik Rezonans Görüntüleme, Galaktografi, Ultrasonografi