CURCUMIN, INCREASING ITS WATER SOLUBILITY BY ULTRASOUND AND PEG

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Sigma Mühendislik ve Fen Bilimleri Dergisi
Volume:35 Issue:1
CURCUMIN, INCREASING ITS WATER SOLUBILITY BY ULTRASOUND AND PEG

CURCUMIN, INCREASING ITS WATER SOLUBILITY BY ULTRASOUND AND PEG

Authors : Huceste ÇATALGİL GİZ, Sevim İŞÇİ, Fatemeh BAHADORİ, Zeynep KALAYCIOĞLU, Barbaros AKKURT

Pages : 47-58

View : 34 | Download : 12

Publication Date : 2017-03-01

Article Type : Research Paper

Abstract :Water solubility of curcumin is increased by PEG in ultrasound medium. Different PEG-curcumin complexes were prepared with and without using ultrasound at 250C. Curcumin concentrations of complexes were determined by UV. The surface charges of PEG-curcumin complexes were investigated by zeta measurements. Critical aggregate concentrations were determined from both UV and zeta potential measurements. Complexes prepared by ultrasound were found to be more compact and homogenous in both size and charge distribution and they also carried more curcumin. Antioxidant capacity of the complexes, determined by DPPH and FRAP methods, were higher than the capacity of curcumin itself.
Keywords : Curcumin, solubility, ultrasound, complex formation, polyethylene glycol

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