ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

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Sigma Mühendislik ve Fen Bilimleri Dergisi
Volume:34 Issue:3
ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

Authors : Burcu TUNCER, Banu MANSUROĞLU, Serap DERMAN

Pages : 453-465

View : 103 | Download : 8

Publication Date : 2016-09-01

Article Type : Research Paper

Abstract :Flavonoids are polyphenols compounds a structural class of mainly natural and a products of secondary metabolism of plants. Flavonoids, which can be found in herbs and trees, act as natural chemopreventives and anticancer agents [1]. As natural products, they have major importance for human life and also have a widespread effect such as antioxidant, antinflammatory, anticarcinogen, antidiabetic [2, 3]. However, bioavailability of this polyphenolic antioxidant have limited because of their high water solubility [4], low absorption, permeability, stability, slow dissolution rate, and light-induced decomposition over time in the physiological medium. In recent years, various methods have been tried to overcome the limitations of flavonoids, including its incorporation into micels and nanoparticles.
Keywords : Nanoparticle, catechin, antioxidant activity, polymeric nanoparticle

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