Comparison of the effects of remifentanil and fentanyl on awakening and hemodynamic parameters in probe curettage cases

Authors : Erol Karaaslan

Pages : 336-344

Doi:10.21673/anadoluklin.1491696

View : 25 | Download : 116

Publication Date : 2024-09-23

Article Type : Research Paper

Abstract :Aim: We aimed to investigate the effects of two different opioids, fentanyl, and remifentanil, on waking parameters, hemodynamic effects, duration of stay in the post-anesthesia care unit (PACU), pain and nausea and vomiting in patients undergoing probe curettage surgery. Methods: Sixty-six patients scheduled for probe curettage surgery were randomly divided into Fentanyl (Group F, n = 33) and Remifentanil (Group R, n = 33) groups. For induction of anesthesia, 2.5 mg/kg propofol was administered as a bolus in both groups, 2.5 mcg/kg fentanyl in Group F and 2-4 mcg/kg i.v. remifentanil in Group R. No muscle relaxant agent was used. The laryngeal mask size was selected according to the patient’s body weight. For induction of anesthesia, 2.5 mg/kg propofol was administered as a bolus in both groups, 2.5 mcg/kg fentanyl in Group F, and 2-4 mcg/kg i.v. remifentanil in Group R. No muscle relaxant was used. The laryngeal mask size was selected according to the patient’s body weight and the cuff pressure was adjusted to 60 cm H2O using a manometer. Results: The demographic data of both groups were similar in our study. Extubation time was shorter in Group R. The difference between the groups was significant (p<0.001). The awakening time was also significantly shorter in Group R (p<0.001). Among the hemodynamic data, MAP values were lower in Group R at T1, T3, and T5 time intervals. HR values were significantly lower in Group R. There was a statistically significant difference between the groups in both time intervals (p: 0.014, p: 0.037) Conclusions: In our study, remifentanil provided better hemodynamic stability, shorter extubation and awakening times, and lower incidence of nausea and vomiting than fentanyl in probe curettage cases. Therefore, we suggest that the use of remifentanil with supraglottic airway devices is a good alternative in anesthesia management.
Keywords : Anesteziden uyanma, fentanil, günlük cerrahi, küretaj, laringeal maske havayolu, remifentanil