Relationship between deep vein thrombosis and serial chest computerized tomography severity scores in COVID-19 patients

Authors : Burcu Akman, Ahmet Turan Kaya, Mustafa Çapraz, Mustafa Cihangiroğlu

Pages : 197-210

Doi:10.21673/anadoluklin.1493434

View : 42 | Download : 86

Publication Date : 2025-05-29

Article Type : Research Paper

Abstract :Aim: We aimed to evaluate risk factors for deep vein thrombosis (DVT) in the lower extremities veins in COVID-19 patients and the relationship between DVT and chest Computed Tomography severity scores (CT-SS). To our knowledge, our study is the first to investigate the relationship between the occurrence of DVT and serial chest CT-SS in COVID-19 patients. Methods: We retrospectively analyzed 131 COVID-19 patients (≥18 years) admitted to our hospital. Two radiologists examined chest CT scans and calculated CT-SS using a visual scoring system. Color Doppler ultrasounds of lower extremity veins were performed for DVT. CT Pulmonary Angiographies (CTPA) were performed on patients clinically suspected of pulmonary embolism (PE). Results: A total of 131 patients were included in our study. 71/131 (54.2%) of the patients were male. 18/131 (13.7%) patients were treated in ICU, and 18 (13.7%) patients died. 21/131 (16%) patients had DVT in their lower extremities. Chest CTA was performed in 44/131 (33.6%) patients, and PE was detected in 10/44 patients (22.7%). PE was considerably more common in patients with DVT (p = 0.009). The occurrence of DVT was significantly associated with high first chest CT-SS (p=0.002). However, there was no association between the DVT and the second and third CT-SS. Significant associations were found between the development of DVT with elevated serum D-Dimer, CRP, and fibrinogen levels (p<0.001; p=0.014; p=0.031). Conclusion: The risk of DVT is higher in COVID-19 patients with diffuse pulmonary involvement on chest CT at admission.
Keywords : Bilgisayarlı tomografi anjiografi, COVID-19, doppler ultrason, venöz tromboz

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