Evaluation of carotid intima-media thickness of female fibromyalgia patients and determination of their relationship with disease activity, severity of fibromyalgia, anxiety and depression levels

Authors : Mehmet BÜYÜKŞİRECİ, Dilek EKER BÜYÜKŞİRECİ, Ayşe Gülşen DOĞAN

Pages : 47-52

Doi:10.38053/acmj.1205466

View : 24 | Download : 15

Publication Date : 2023-01-20

Article Type : Research Paper

Abstract :Aim: Carotid artery intima-media thickness is thought strong predictor of cardiovascular diseases. To evaluate the common carotid artery intima-media thickness insert ignore into journalissuearticles values(CCIMT); in female patients with fibromiyalgia insert ignore into journalissuearticles values(FM); and determine its relationship with disease activity, severity of fibromyalgia, anxiety and depression levels. Material and Method: Thirty nine patients who had fibromyalgia syndrome according to 2016 American College of Rheumatology insert ignore into journalissuearticles values(ACR); classification criteria and 41 healthy controls were included. Pain level and disease activities were assessed with Numerical Rating Scale insert ignore into journalissuearticles values(NRS); and Fibromyalgia Impact Questionnairre insert ignore into journalissuearticles values(FIQ); respectively. According to ACR 2016 classification criteria, Widespread Pain Index insert ignore into journalissuearticles values(WPI);, Symptom Severity Score and Hospital Anxiety and Depression Scale insert ignore into journalissuearticles values(HADS); were performed. The LDL , HDL and Triglyceride levels were evaluated. Bilateral common carotid artery intima-media thicknesses insert ignore into journalissuearticles values(CCIMT); were performed by a blind radiologist to the groups of participants. Results: Age, weight and height were similar between groups insert ignore into journalissuearticles values(p>0.05);. Triglyceride level was significant higher in patients with FM insert ignore into journalissuearticles values(p=0.001);. HDL and LDL levels were similar between groups insert ignore into journalissuearticles values(p=0.297, p=0.061);. Bilateral CCIMT was significantly higher in patients with FM insert ignore into journalissuearticles values(p<0.001);. Bilateral CCIMT were found positively correlated with age in FM group insert ignore into journalissuearticles values(r=0.390, p=0.014, r=0.404, p=0.011 respectively);. There were found no correlations between bilateral CCIMT, height, weight, triglyseride level, LDL level, FIQ, NRS, WPI, Symptom Severity Score, HADS scores. . Conclusion: In FM patients, bilateral CCIMTs were found increased compared to healthy controls. No associations were found between CCIMT, LDL, triglyceride levels, disease activity and pain level, anxiety and depression level in patients with FM. 
Keywords : Fibromiyalgia, common carotid artery intima media thickness, disease activity, anxiety, depression