A recovered patient after myocardial injury related to Covid-19; a case report

Authors : Recep ALANLI, Murat Bülent KÜÇÜKAY, Serkan YALÇIN, Şahin MURSEL, Bülent Ahmet BEŞİRBELLİOĞLU

Pages : 125-127

Doi:10.20492/aeahtd.744574

View : 33 | Download : 8

Publication Date : 2020-08-31

Article Type : Other Papers

Abstract :ACE2 receptors are reported to have an important role in myocardial injury in Covid-19. Direct myocardial toxic effect of virus, myocarditis, cytokine injury, microangiopathic injury related to virus infection may cause myocardial injury and eventually troponin levels increase. Those mechanisms are; unstable plaques in coronary arteries resulting in myocardial hypoxia, upregulation of ACE2 receptors in coronary arteries and cardiac tissue, direct toxic effect of virus towards myocytes, systemic inflammation, myocardial interstitial fibrosis, excessive immune response to interferon, increased cytokine release from helper T lymphocytes which lead to myocardial injury. In this reported case, clinical course was mild and outcome was good, patient was followed in ward and he did not need intensive care.
Keywords : covid 19, myocardial injury, troponin