MALE BREAST CANCER: A RETROSPECTIVE ANALYSIS OF SINGLE CENTER RESULTS

Authors : Hakan BAYSAL, Ayşegül ERGÜN, Begümhan BAYSAL, Zeynep Çağla TARCAN, Mehmet Sait ÖZSOY, Fatih BÜYÜKER, Orhan ALİMOĞLU

Pages : 103-108

Doi:10.20492/aeahtd.1335516

View : 145 | Download : 75

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :AIM Male breast cancers insert ignore into journalissuearticles values(MBC);, constituting less than 1% of all breast carcinomas, are relatively rare. The average age of diagnosis is between 60-70 years and can affect males of all ages. In this study our aim was to present the clinicopathological characteristics, treatment, and survival outcomes of patients who were treated and followed up for ten years in out clinic, in accordance with literature. MATERIAL AND METHOD Records of MBC patients who were followed and treated at our clinic between January 2014 and January 2023 were examined retrospectively using the hospital database. Clinicopathological characteristics, treatments performed, overall and disease-free survival rates were analyzed. RESULTS A total of 19 patients were included in the study insert ignore into journalissuearticles values(mean age: 75.9±11.5, range: 57-96);. Four patients with distant metastasis and other system malignancies at the time of diagnosis were excluded. The mean follow-up period was 43.8 months. The most common location of the tumor was to be the retroareolar region insert ignore into journalissuearticles values(63.2%);. BRCA2 gene mutation analysis was positive in three patients. Eleven patients insert ignore into journalissuearticles values(57.9%); were at Stage 3. Eleven patients had invasive ductal carcinoma. Twelve patients belong to the luminal B subtype. Among the 13 patients who underwent axillary dissection 9 insert ignore into journalissuearticles values(69.2%); had lymph node involvement. Patients who developed distant metastasis had higher overall mortality and cancer-specific mortality. The body mass index insert ignore into journalissuearticles values(BMI); of deceased patients was lower than that of surviving patients during the follow-up period. Age group above 75 years had lower overall survival insert ignore into journalissuearticles values(log-rank p=0.0064); and cancer-specific survival insert ignore into journalissuearticles values(log-rank p=0.011);. CONCLUSION In our study, we found that distant metastasis significantly affected the survival. Although male breast cancers are rare, early diagnosis, as in women, positively influences overall and disease-free survival.
Keywords : erkek meme kanseri, sağkalım, metastaz, mastektomi

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