Evaluation of PLEVA and PLC Patients: Two Decades of Clinical Experience

Authors : Nermin Karaosmanoğlu, İçim Kömürcügil Yiğit, Berkay Dirliktutan, Zülküf Arslan, İsmail Yüksel, Pınar Özdemir Çetinkaya

Pages : 25-29

Doi:10.20492/aeahtd.1645084

View : 18 | Download : 12

Publication Date : 2025-05-04

Article Type : Research Paper

Abstract :Aim: The aim of this study is to analyze the clinical and demographic characteristics, histopathological findings, and treatment responses of patients with pityriasis lichenoides. Additionally, the study aims to investigate the differences between pediatric and adult patients. Material and Method: The data of 47 patients with pityriasis lichenoides, followed up at the Dermatology Clinic of Ankara Training and Research Hospital between 01.08.2004 and 01.08.2024, were retrospectively analysed. The patients were classified as pityriasis lichenoides chronica and pityriasis lichenoides et varioliformis acuta. Clinical, demographic, and histopathological characteristics, as well as treatment responses, were evaluated. The patients were divided into pediatric ( 18 years) groups for comparison. In statistical analyses, a p-value of <0.05 was considered significant. Results: Sixty-six percent of the patients were female, and 34% were male, with a mean age of 35.28±18.96 years. The median disease duration was 14 months, and the median time to diagnosis was 3 months. The most commonly affected areas were the trunk and extremities (68.1%). Relapses were observed in 42.6% of the patients. The most frequently detected histopathological findings were perivascular lymphocytic infiltration (87.8%) and lymphocytic exocytosis (80.5%). All patients were treated with topical corticosteroids, and 95.7% received narrow-band UVB phototherapy. The complete response rate was 40.4%, the partial response rate was 51.1%, and no response was observed in 8.5% of the patients. In pediatric patients, the disease duration was significantly shorter than in adults (p=0.026). Conclusion: Pityriasis lichenoides has a longer duration in adults, while pediatric patients are diagnosed earlier. Narrow-band UVB phototherapy is an effective treatment option for both children and adults. More prospective studies are needed for the management of pityriasis lichenoides.
Keywords : pityriasis likenoides, fototerapi, doksisiklin