Comparison of the effects of sperm selection methods on assisted reproduction outcomes in male infertility

Authors : Gönül ÖZER, Sevinç ÖZMEN

Pages : 166-172

Doi:10.33719/yud.2023;18-2-1247568

View : 18 | Download : 29

Publication Date : 2023-06-27

Article Type : Research Paper

Abstract :Objective: To compare physiological intracytoplasmic sperm injection insert ignore into journalissuearticles values(PICSI); and the hypoosmotic swelling test insert ignore into journalissuearticles values(HOST); sperm selection techniques in terms of embryo development, implantation rate and live birth rates in cases of severe or moderate oligoastheneospermia. Materials and Methods: The electronic material and files of cases admitted to the Medipol University IVF Centre between 2013 and 2022 were analyzed retrospectively. This research included a total of 143 cases with moderate or severe oligoasthenospermia, 80 cases with PICSI as sperm selection technique and 63 cases with HOST as sperm selection technique. Cases of severe or moderate oligoasthenospermia as defined by the World Health Organisation insert ignore into journalissuearticles values(WHO); are included in this study. The demographic parameters of both groups, including female age, paternal age, duration of infertility, AMH insert ignore into journalissuearticles values(anti-Mullerian hormone);, body mass index insert ignore into journalissuearticles values(BMI);, endometrial thickness, and the number of prior attempts, were analyzed. Implantation, pregnancy loss, and rates of live births were compared between two groups. Results: Female age, paternal age, AMH, endometrial thickness, BMI, and the number of previous trials were similar between the groups included in the study. There were not any significant differences between the groups in terms of fertilization insert ignore into journalissuearticles values(.18±6.92 vs 9.11±6.35, p=0.345);, TQ-GQ blastocyst development insert ignore into journalissuearticles values(2.36±2.40 vs 1.64±2.35, p=0.097);, and the number of embryos transferred insert ignore into journalissuearticles values(1.59±0.50 -1.76±0.44 p= 0.141);. The live birth rates between the PICSI and HOST groups did not vary statistically insert ignore into journalissuearticles values(p=0.790);, however, the rate of implantation was significantly higher in the HOST group insert ignore into journalissuearticles values(p=0.043);. Sperm selection by PICSI or HOST method did not affect fertilization, TQ-GQ blastocyst development, and the rates of pregnancy loss and live birth. Conclusion: Although there were not any differences in embryo development, pregnancy loss, and live birth rates comparing the two methods, the HOST group had a higher implantation rate.
Keywords : PICSI, HOST, Erkek infetilitesi