Practical Application and Influence of “Avigen duck” Immunomodulator to White Pekin Ducks Humoral Immune Factors

Authors : Rumen KARAKOLEV, Tsvetoslav KOYNARSKI, Preslava PETROVATSENIN, Reneta PETROVA

Pages : 10-17

Doi:10.29133/yyutbd.1148392

View : 17 | Download : 6

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :Factors of non-specific immunity are responsible for protecting birds from a number of viruses and bacteria. Bactericidal proteins are played here lysozyme and complement, interferon, as well as beta-lysine. Adding appropriate active compounds to the bird\`s diet to activate the innate immune response are subject to studies by many authors. The practical application and influence of the \`Avigen Duck\`. immunomodulator in the cultivation of White Pekin ducks aims to clarify the dynamics of the indicators. It was found that the ducks treated with the immunomodulator had higher non-specific protection expressed in the values of the observed indicators. Complement activity for the experienced group insert ignore into journalissuearticles values(529.45 ± 17,85 CH50); is significantly higher than that of untrained birds insert ignore into journalissuearticles values(308.56 ± 10.19 CH50);, on the 30th day of their lives insert ignore into journalissuearticles values(P <0.001);. Lysozyme values for the experienced group insert ignore into journalissuearticles values(6.34 ± 0.86 mg L-1); is more than twice as high as its concentration in control birds - 2.52 ± 0.59 mg L-1. At 30 days of age, the mean concentration of IFN γ in the control group of ducks was 108.86±6.12 pg ml-1, and in the experimental group treated with immunomodulator - 518.06±12.80 pg ml-1, accompanied by an increase in the values of IL-2 and IL-6 and beta-lysine activity. These data show that, despite the short life of the ducks, the concentrations of the investigated factors of non-specific immunity increase significantly and statistically reliably, even after a single treatment with immunomodulator \`Avigen Duck\`. The practical application of the immunomodulator in the duck diet has a strong effect on their non-specific immunity.
Keywords : Beta lysinе, Complement system, IFN γ