Histopathological Results of Suspicious Nodules in the Patients with Hashimoto Thyroiditis

Authors : Sevilay OZMEN, Havva Tugba KİPER YILMAZ, İlknur CALIK, Yusuf CAN, Özge TİMUR, Şenay ARIKAN DURMAZ, Eşref KABALAR, Ayşe ÇARLIOĞLU, Kenan ÇADIRCI, Aykut TURHAN

Pages : 8-11

View : 21 | Download : 9

Publication Date : 2020-01-01

Article Type : Research Paper

Abstract :The most endocrinologists in routine practice are used to Bethesda classification for evaluation of thyroid nodule in fine needle aspiration biopsy insert ignore into journalissuearticles values(FNA);. It is accepted that FNA biopsy is an accurate diagnostic and gold standard test. However, false-positive diagnosis may sometimes occur as a patient with a ‘malign’ lesion is found incorrectly rather than an actually benign lesion on histological examination. Hashimoto’s thyroiditis probably is the most common cause of false-positive cytology. The aims of present study evaluate retrospectively postoperatively biopsy results in patients with Hashimoto disease have a thyroidectomy. Results of totally 29 patients with Hashimoto thyroiditis achieved from our hospital records. All of the patients had undergone totally or subtotals thyroidectomy. We are-evaluated retrospectively biopsy results postoperatively. We compared their preoperative FNA results. We detected 24.1% papillary thyroid cancer in seven patients insert ignore into journalissuearticles values(mean age 45.5±11.9 year);, 44.8% nodular goitre in 13 patients insert ignore into journalissuearticles values(mean age 45.8±4.9 year);, 13.7% adenomatous nodule in four patients insert ignore into journalissuearticles values(mean age 43.5±14.4 year);, 3.4% hurtle cell adenoma in one patient with 56 years old. But, 14% in four patients with Hashimoto thyroiditis insert ignore into journalissuearticles values(mean age 41.5±13.1 year); were redundantly operated due to atypia of undetermined significance in FNA. Although Hashimoto disease is a benign diagnosis, its misclassification as atypia of undetermined significance in FNA accounts for some false-positive errors. The cytopathologists can frequently be interpreted as atypia of undetermined significance instead of Hashimoto’s thyroiditis. Therefore, result of atypia of undetermined significance in FNA may lead unnecessarily concern among with the endocrinologists. More importantly, our results demonstrated that high papillary thyroid cancer rate was found postoperatively in suspicious nodules evolved background Hashimoto thyroiditis.
Keywords : Hashimoto thyroiditis, Nodules, Fine needle aspiration biopsy, Papillary thyroid cancer