Microbiological Analysis of Secondary Bacterial Infections in Patients Infected with the SARS-CoV-2 Virus

Melek BİLGİN; Eşe BAŞBULUT; Hacer İŞLER; Cemanur AYGÜN

doi:10.19127/bshealthscience.867150

Microbiological Analysis of Secondary Bacterial Infections in Patients Infected with the SARS-CoV-2 Virus

Authors : Melek BİLGİN, Eşe BAŞBULUT, Hacer İŞLER, Cemanur AYGÜN

Pages : 270-273

Doi:10.19127/bshealthscience.867150

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Publication Date : 2021-09-01

Article Type : Research Paper

Abstract :Accumulating evidence shows that secondary infection increases the risk of disease severity in respiratory diseases. There have been few studies about secondary infections among COVID-19 patients. Therefore we aimed to investigate prevalence, predisposing factors and causative organisms associated with COVID-19 secondary infection. This study was conducted at Training and Research Hospital in Samsun Turkey between March 15, 2020 and June 15, 2020. Hospitalized COVID-19 patients confirmed with Reverse Transcription Polymerase Chain Reaction insert ignore into journalissuearticles values(RT-PCR); were included in this study. Various clinical specimens insert ignore into journalissuearticles values(urine, sputum, endotracheal aspirate, blood etc.); of these patients have been sent to the microbiology laboratory were evaluated retrospectively. During the study period, 270 patients have been diagnosed COVID‐19 confirmed with PCR. The bacterial secondary infection rate among COVID-19 patients was 4% insert ignore into journalissuearticles values(11 of 270);. The mortality rate among intensive care unit insert ignore into journalissuearticles values(ICU); patients with secondary infections was 80%. The most common secondary infection was urinary tract infection followed by bacteremia, and pneumonia. The most common isolated bacteria is Escherichia coli insert ignore into journalissuearticles values(E. coli); followed by coagulase-negative staphylococci insert ignore into journalissuearticles values(CoNS);. Among COVID-19 patients, secondary infection may signiﬁcantly inhibit the immune system of host and leads to signiﬁcant morbidity and mortality. This is problematic and especially impacts patient clinical management, infection control, and antimicrobial stewardship programs. Therefore, further studies are needed to identify the possible pathogens and to evaluate the influence of secondary infections on the severity of SARS-CoV-2 infection.
Keywords : COVID 19, SARS CoV 2, Secondary infection

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