Association of sarcopenia with age-related macular degeneration in the very elderly

Authors : Zeynep Katipoğlu, Bilal Katipoğlu, Meydan Turan

Pages : 341-346

Doi:10.17826/cumj.1625475

View : 108 | Download : 117

Publication Date : 2025-06-30

Article Type : Research Paper

Abstract :Purpose: The aim of this study was aimed to investigate the association between age-related macular degeneration and sarcopenia in the oldest-old population, constituting individuals aged ≥80 years. Material and Methods: This retrospective study was conducted in the ophthalmology and geriatric departments of a training and research hospital in 2023 and 2024. Participants aged ≥80 years who were admitted to the ophthalmology outpatient clinic for any reason were included in the study. Results: The study population comprised 311 individuals aged 80 years or older and the prevalence of age-related macular degeneration was 20.5% (n=64). The mean age of the patients diagnosed with age-related macular degeneration (AMD) was 85.9 years (±3.8), while the mean age of the control group was 85.8 years (±3.9). Of the patients diagnosed with age-related macular degeneration, 34 were female and 30 were male. The Deyo-Charlson Comorbidity Index (D-CCI) values were 1.77 in the age-related macular degeneration group and 1.85 in the control group. The prevalence of sarcopenia was significantly higher in patients with age-related macular degeneration (89.1% vs. 52.6%). Conclusion: This study demonstrates that sarcopenia is independently associated with age-related macular degeneration in the oldest-old population. These findings highlight the significance of sarcopenia management in the prevention and management of age-related macular degeneration.
Keywords : oksidatif stres, sarkopeni, yaşa bağlı makula dejenerasyon, inflamasyon

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