Triglyceride-glucose index as a potential biomarker in acute central serous chorioretinopathy

Authors : Ali Osman Gündoğan, Naciye Tora, Selman Belviranlı, Mehmet Adam, Günhal Şatırtav, Refik Oltulu

Pages : 586-593

Doi:10.17826/cumj.1625502

View : 40 | Download : 71

Publication Date : 2025-09-30

Article Type : Research Paper

Abstract :Purpose: The aim of this study is to compare triglyceride-glucose index (TGI) levels in patients with acute central serous chorioretinopathy (CSCR), chronic CSCR, and healthy controls, and to the value of TGI in indicating the risk of acute CSCR. Materials and Methods: This retrospective study included 20 patients with acute CSCR, 20 patients with chronic CSCR, and 40 healthy controls. The TGI was calculated using fasting plasma triglyceride and glucose levels, and values were compared between groups. A receiver operating characteristic (ROC) curve was used to calculate the optimal TGI cut-off value, sensitivity, and specificity between the acute CSCR and control groups. Results: There were no statistically significant differences between the groups in terms of age and sex. The TGI value was 8.48±0.29 in the control group, 8.91±0.34 in the acute CSCR group, and 8.59±0.40 in the chronic CSCR group (p<0.001 for control vs. acute CSCR; p=0.703 for control vs. chronic CSCR; p=0.011 for acute vs. chronic CSCR). The optimal ROC cut-off value of TGI between the control and acute CSCR groups was calculated as 8.74 with 75% sensitivity and 85% specificity (AUC: 0.835, p<0.001, 95% CI 0.719-0.951). Conclusion: Caution should be exercised in patients with acute CSCR regarding the presence of underlying cardiovascular disease. Additionally, this biomarker, which can be easily measured through routine blood testing, may serve as a potentia
Keywords : Santral Seröz Koryoretinopati, Trigliserid, Glukoz, Trigliserid-Glukoz İndeksi, Kan-Lipid Profili

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