Retrospective Evaluation of In-Hospital and Thirty-Month Mortality Parameters in Cases of Acute Coronary Syndrome

Authors : Bahadir ALAN, Latife KAYIKÇIOĞLU, İrmak SAYIN ALAN

Pages : 80-91

Doi:10.56016/dahudermj.1112297

View : 20 | Download : 10

Publication Date : 2022-07-29

Article Type : Research Paper

Abstract :Objectives: The aim of this study is to retrospectively assess, from the hospital records of patients, the clinical data of patients and the treatment strategies practiced on patients who were diagnosed as Acute Coronary Syndrome insert ignore into journalissuearticles values(ACS); and hospitalized and treated in the Hospital of Faculty of Medicine to research the effect of these data on occurrence of cardiovascular events and 30 months mortality. Methods: It is a retrospective screening study in which patients hospitalized with the diagnosis of ACS between June 2007 and December 2008 in the Hospital of Faculty of Medicine Cardiology Clinic are evaluated by using patient file information and electronic data recording system information, and by calling patients. In-hospital and long-term follow-up deaths were the endpoints of the study. Statistical analysis was performed using SPSS insert ignore into journalissuearticles values(Version 15.0);. Results: 985 patients were included in the study who were diagnosed as ACS, hospitalized and treated in the hospital. The categorization of the patients subjected to the analysis insert ignore into journalissuearticles values(n:901); according to their diagnosis is as follows: 339 insert ignore into journalissuearticles values(38%); cases diagnosed as UAP, 206 insert ignore into journalissuearticles values(23%); cases diagnosed as NSTEMI, and 356 insert ignore into journalissuearticles values(39%); cases diagnosed as STEMI. 78,4 % of cases were male while 21,6 % were female. It was found that cases with hypertension, hyperlipidemia, obesity risk factor, and with a history of cardiovascular disease fall into the NSTEMI and UAP groups with a larger proportion. Among the groups, the UAP diagnosed cases have the largest and the STEMI diagnosed cases have the smallest ratio of using medicine groups such as beta blocker, calcium-canal blocker, ACE inhibitor, ARB, diuretic, statin, fibrate and nitrate before being hospitalized. In-hospital mortality was frequently encountered with a percentage of 7.6 % in STEMI cases, 2.4 % in NSTEMI cases, and 0.6 % in UAP cases. 30-months of follow-up data were obtained in all diagnosis groups for long-term mortality assessment. 70 insert ignore into journalissuearticles values(7.8 %); deaths were observed within the follow-up. According to diagnosis groups, death was observed in 22 insert ignore into journalissuearticles values(6.5 %); of UAP cases, 22 insert ignore into journalissuearticles values(10.7 %); of NSTEMI cases, and 26 insert ignore into journalissuearticles values(7.3 %); of STEMI cases. Correlation between long-term survival insert ignore into journalissuearticles values(30 months); and in-hospital statin usage and statin usage in discharge was not significant insert ignore into journalissuearticles values(p value respectively 0.1 and 0.16);. Correlation between an approximate 30-months-survival and in-hospital ACE inhibitor/ARB inhibitor usage and ACE inhibitor/ARB inhibitor usage during discharge was significant insert ignore into journalissuearticles values(p = 0.007 and p = 0.004);. It is also found that there was a significant correlation between survival in the same period of time and in-hospital beta blocker usage insert ignore into journalissuearticles values(p = 0.01);. There was not a significant correlation between beta blocker usage during discharge and long-term survival insert ignore into journalissuearticles values(p = 0.779);. Conclusion: Results of the unicentral retrospective scanning study which involves 901 ACS diagnosed patients prove to be similar to the ones obtained from GRACE and Euro Heart Survey prospective studies which were carried out in multi-central environment and among outnumbered patients.
Keywords : Acute Coronary Syndrome, Beta Blocker, Mortality, RAS Blocker, Statin