Neutrophil-Lymphocyte Ratio as a Mortality Predictive Paramater In Patıents Wıth Out-of-Hospital Cardiac Arrest

Belgin AKILLI; Hüseyin MUTLU; Yahya Kemal GÜNAYDIN; Ramazan KÖYLÜ; Levent OKTAR; Basar CANDER

Neutrophil-Lymphocyte Ratio as a Mortality Predictive Paramater In Patıents Wıth Out-of-Hospital Cardiac Arrest

Authors : Belgin AKILLI, Hüseyin MUTLU, Yahya Kemal GÜNAYDIN, Ramazan KÖYLÜ, Levent OKTAR, Basar CANDER

Pages : 15-20

View : 46 | Download : 16

Publication Date : 2021-04-15

Article Type : Research Paper

Abstract :Introduction:The rates of out-of-hospital cardiac arrest insert ignore into journalissuearticles values(OHCA); are increasing day by day in a progressive manner. Despite all the improvements in care after cardiac arrest, the majority of fatalities occur in the first 24-hours following the cardiac arrest.In recent years, the ratio of the peripheral neutrophils to lymphocytes insert ignore into journalissuearticles values(NLR); has been accepted as a prognostic marker in many diseases. We also aimed to investigate the correlation of the NLR with mortality in patients with OHCA.Methods:The study design was planned by retrospective scanning of all OHCA patients with return of spontaneous circulationinsert ignore into journalissuearticles values(ROSC);. The demographic features and laboratory data were recorded. The survival rates for the 24-hours and 14-days were calculated.Results: 91 patients were included out of 191 cases who had returned from OHCA to spontaneous circulation. When the patients who had died and survived in the first 24-hours were compared, significant differences were found between the neutrophil counts, NLR, lactate and arrest rhythms on admission insert ignore into journalissuearticles values(p<0.05);. The survival rates calculated by Kaplan Meier curves were significantly lower in the group with NLR values lower than 3.05 insert ignore into journalissuearticles values(Log Rank 5.07, p=0.02);. With the multivariable Cox-regression model, it was determined that the NLR value being lower than 3.05, is a predictive factor for the 24-hour mortality independent of age, gender, blood lactate and creatinine values and the arrest rhythm on admission insert ignore into journalissuearticles values(Hazard Ratio: 0.34 insert ignore into journalissuearticles values(0.15-0.79);, p=0.01);.Conclusion: Among the OHCA patients with ROSC, low NLR levels on admission is an independent predictor of mortality in the first 24-hours.
Keywords : emregency, NLR, resuscitation

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