Evaluation of the relationship between the frequency of attacks and vitamin levels in patients admitted to the emergency department with migraine headache

Authors : Dilek ATİK, Hasan Burak KAYA

Pages : 25-28

View : 23 | Download : 13

Publication Date : 2021-04-15

Article Type : Research Paper

Abstract :Introduction: Migraine is a common multifactorial, neurovascular primary headache disorder that develops due to the increased excitability of the central nervous system insert ignore into journalissuearticles values(CNS); and causes limitations in the quality of life of individuals. In this study, it was aimed to evaluate the relationship between the frequency of attacks and vitamin levels of patients who had migraine attacks and presented to the emergency department with a migraine attack. Method: The study is a retrospective cross-sectional study. 54 patients who were diagnosed with migraine headache according to the International Headache classification between January 1, 2019, and January 1, 2020, in the Emergency Medicine clinic of Yozgat Bozok University insert ignore into journalissuearticles values(Group 1);. There was no history of systemic diseases such as diabetes mellitus, hypertension, heart disease, or goiter. The control group consisted of individuals who were examined for a general medical examination during the same period, whose migraine history was not in their anamnesis and history, and who did not receive vitamin supplements insert ignore into journalissuearticles values(Group 2);. Mann-Whitney U test was used in statistical evaluations according to the status of the statistically nonparametric variables and the correlated variables were categorical insert ignore into journalissuearticles values(nominal or ordinal); and numerical independent group. Spearman rank correlation method was used in nonparametric data for correlations between data. The results were evaluated for a significance level of p <0.05. Results: A total of 51.4% insert ignore into journalissuearticles values(n = 54); migraine patients insert ignore into journalissuearticles values(Group 1); and 48.6% insert ignore into journalissuearticles values(n = 51); healthy control group insert ignore into journalissuearticles values(Group 2); were included in the study. Of group 1 patients, 85.7% insert ignore into journalissuearticles values(n = 46); were female and 14.3% insert ignore into journalissuearticles values(n = 8); were male. Vitamin B12, Folate and Vitamin D levels were significantly lower in Group 2 insert ignore into journalissuearticles values(<0.05);. While there was a moderate negative correlation with vitamin D level, there was a weak negative correlation with vitamin B12 and Folate parameters insert ignore into journalissuearticles values(<0.05);. Vitamin D level was found to be significantly lower in migraine patients with aura in the migraine patient group insert ignore into journalissuearticles values(<0.05);. Conclusion: Especially vitamin D, vitamin B12, and folate levels have an important place among the causes of migraine headaches. Besides, we think that low Vitamin D level is important in migraine-type with aura. Therefore, prospective studies are needed, especially on vitamin D and migraine subgroups.
Keywords : vitamin D, vitamin B12, Migraine, emergency department