Can We Predict the Width of the Infarct Area in Patients with Acute Ischemic Stroke Using Near Infrared Spectrophotometry?

Authors : Özlem BİLİR, Gökhan ERSUNAN, Asım KALKAN

Pages : 43-47

View : 25 | Download : 8

Publication Date : 2021-08-31

Article Type : Research Paper

Abstract :Background and Purpose: The purpose of this study to determine whether an association exists between near infrared spectrophotometry insert ignore into journalissuearticles values(NIRS); measurements and affected brain tissue by using NIRS to measure cerebral oxygenations in patients brought to the emergency department with acute ischemic stroke insert ignore into journalissuearticles values(AIS);. Methods: Thirty-one patients diagnosed with ischemic stroke at diffusion weighted magnetic resonance imaging insert ignore into journalissuearticles values(MRI); of the brain, aged or over, with no history of ischemic or hemorrhagic stroke and diagnosed at the Recep Tayyip Erdoğan University Education and Research Hospital emergency department, Turkey, were included in the study. Patients with foci of intracranial hemorrhage at cranial computerized tomography insert ignore into journalissuearticles values(CT); of the brain and no ischemic area identified at brain diffusion MRI were excluded. Cerebral saturation was recorded after being measured for at least 10 min with an INVOS 5100C cerebral/ somatic oximeter insert ignore into journalissuearticles values(Covidien);. Results: Mean age of the 31 patients presenting to the emergency department with AIS was 76.32 ± 10.26. Sixteen insert ignore into journalissuearticles values(51.6%); were female. Mean Glasgow Coma Score insert ignore into journalissuearticles values(GCS); was 12.68 ± 3.16. Mean oxygenation values of the ischemic areas in these patients were 57.03 ± 9.03 insert ignore into journalissuearticles values(min: 40, max: 81);, while the mean measurement from areas with no cerebral changes was 67.13 ± 9.64 insert ignore into journalissuearticles values(min: 54, max: 89); insert ignore into journalissuearticles values(p<0.001);. Mean dimension of the ischemic areas visualized at diffuse MRI was 979.77 ± 635.85 mm2 insert ignore into journalissuearticles values(min: 43, max: 2180);. A positive moderate correlation was observed between ischemic area dimensions and cerebral oximeter values for those areas insert ignore into journalissuearticles values(r=0,597, p=<0.001);. The linear regression model established between patients’ ischemic area diameters and level of decrease in cerebral oxygenations revealed a fall in cerebral oxygenation of 5.945 + insert ignore into journalissuearticles values(0.005 x infarct area insert ignore into journalissuearticles values(mm2););. Conclusion: We conclude that that greater the fall in cerebral oxygenation levels the greater the dimensions of the ischemic area. NIRS may be a method that can be used in predicting width of infarct area in patients with AIS.
Keywords : Acute Ischemic Stroke, Near Infrared Spectrophotometry, Infarct Area