Lectin Affinity Based Recognition Nanomaterial for Glucose

Authors : Kevser KUŞAT, Cansu KURU, Fulden ULUCAN, Sinan AKGÖL

Pages : 179-190

Doi:10.15671/hjbc.710711

View : 25 | Download : 11

Publication Date : 2020-04-19

Article Type : Research Paper

Abstract :Glucose is an important biomolecule because it is an important source of energy for cells and is used as an intermediate/metabolic agent. Selective recognition of glucose is important for diagnosing many metabolic diseases. In this study, lectin ligand insert ignore into journalissuearticles values(Con A); attached pinsert ignore into journalissuearticles values(GMA); nanopolymer was synthesized and characterized. The best interaction of pinsert ignore into journalissuearticles values(GMA);-ConA nanopolymer and glucose was determined to be 10mM glucose concentration at pH = 8.0. In the selectivity assay, pinsert ignore into journalissuearticles values(GMA);-Con A was found to be 2-fold selective for glucose than galactose. Lectin affinity based nanopolymeric system that is selective, with high surface area, low cost and highly biocompatible with high adsorption capacity has been developed for recognition of glucose.
Keywords : Nanotechnology, Glucose, Lectin Affinity Chromatography