A Retrospective Study on Urinary Tract Infection Agents Isolated from Children and Their Antibiotic Susceptibility

Authors : Neslihan İDİL, Esra Deniz CANDAN, Abbas Yousefi RAD

Pages : 265-274

Doi:10.15671/hjbc.639411

View : 20 | Download : 8

Publication Date : 2020-06-15

Article Type : Research Paper

Abstract :Antibiotics are important premises in the treatment of urinary tract infection insert ignore into journalissuearticles values(UTI);. However, the use of antibiotics is an important risk factor causing antibiotic resistance. Antibiotic inappropriate resistance is one of the most important problems of increased uropathogenic resistance, especially in pediatric urology. Deficiencies in empirical prescription practices can make this problem even worse. In this study, the demographic characteristics of pediatric patients, UTI agents, and antibiotic resistance resistance of these agents were retrospectively evaluated by an automated system. The data from 719 UTI agents isolated from children were separately analyzed for four different age groups insert ignore into journalissuearticles values(0-2, 2-6, 6-12, and 12-17);. The most commonly isolated infection agents were Escherichia coli insert ignore into journalissuearticles values(68.01%);, Klebsiella pneumoniae insert ignore into journalissuearticles values(19.75%);, Klebsiella oxytoca insert ignore into journalissuearticles values(3.34%);, Enterobacter cloacae insert ignore into journalissuearticles values(2.23%);, and Pseudomonas aeruginosa insert ignore into journalissuearticles values(1.95%);. Among the age groups, 0-2 age group was quite diverse in terms of infection agents and antibiotic resistance values of these agents were significantly high in this group insert ignore into journalissuearticles values(p<0.05);. Regarding the antibiotic resistance, the most noteworthy ones were the resistance against ampicillin insert ignore into journalissuearticles values(70.2%);, amoxicillin-clavulanate insert ignore into journalissuearticles values(49.0%);, cefixime insert ignore into journalissuearticles values(38.2%);, and trimethoprim/sulfamethoxazole insert ignore into journalissuearticles values(37.1%);. Our study indicated that children in 0-2 age group were under higher risk in terms of UTI agents and their antibiotic resistance but this risk was reduced with increasing age. Moreover, the ratio of girls with UTI was greater than that of boys within 0-2 age group. There was high resistance against cephalosporin, ampicillin, amoxicillin- clavulanate , and trimethoprim/sulfamethoxazole, whereas the resistance against carbapenem insert ignore into journalissuearticles values(imipenem, ertapenem and meropenem); was found to be low and there was no significant increase.
Keywords : Antibiotic resistance, Escherichia coli, Pediatric urology, Urinary tract infection